Mitelman Database Release Notes
To search this database hosted by the ISB-CGC, please visit Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer.
For more detailed information about the Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer, see Mitelman Database.
April 15, 2024
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 77,578
Total number of unique gene fusions 33,895
Total number of genes involved 14,053
January 16, 2024
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Additionally, there was a bug fix related to the result download button.
Updated totals
Total number of cases 77,532
Total number of unique gene fusions 33,802
Total number of genes involved 14,051
October 16, 2023
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
More than 200 new cases were added, in addition to many new gene fusions. A number of genes that were reclassified as pseudogenes have also been removed, resulting in a small net gain in gene and fusion counts.
Updated totals
Total number of cases 77,061
Total number of unique gene fusions 33,711
Total number of genes involved 14,046
August 3, 2023
Added missing data, plus some additional new cases.
Updated totals
Total number of cases 76,835
Total number of unique gene fusions 33,710
Total number of genes involved 14,059
July 17, 2023
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 76,534
Total number of unique gene fusions 33,671
Total number of genes involved 14,056
April 17, 2023
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 76,239
Total number of unique gene fusions 33,968
Total number of genes involved 14,097
January 19, 2023
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 75,312
Total number of unique gene fusions 33,885
Total number of genes involved 14,091
October 17, 2022
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 74,420
Total number of unique gene fusions 33,621
Total number of genes involved 14,068
July 27, 2022
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 73,930
Total number of unique gene fusions 33,457
Total number of genes involved 14,061
June 6, 2022
Enhancements and New Features
Mitelman Database Now Includes Genomic Coordinates
Until June 2022, the resulting genetic location information retrieved from the database was only displayed in karyotypes. Now, genomic coordinates are also displayed. Thanks to procedures incorporated from the web-based tool CytoConverter, karyotypes are converted to genomic coordinates and can be optionally viewed by the Mitelman Database user.
The user has the option of viewing the genomic coordinate information for either individual karyotypes or for multiple karyotypes in a search result. For individual karyotypes, the corresponding chromosome and its start and end position are given. In addition, the type of imbalance (gain or loss) is noted. For multiple karyotypes in the search results, net imbalances across the selected group are displayed in chart, ideogram or tabular format; information includes the chromosome affected, start and end positions, and whether the segment has been lost or gained.
April 18, 2022
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 72,718
Total number of unique gene fusions 32,962
Total number of genes involved 14,016
January 18, 2022
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 72,421
Total number of unique gene fusions 32,855
Total number of genes involved 14,022
Enhancements and New Features
According to the recent recommendations of The Hugo Genome Nomenclature Committee (HGNC), the designations of all fusion genes have been changed from forward slash (/) to double colon (::). This affects the searches: “Gene Fusions”, Clinical Associations”, and “Recurrent Chromosome Aberrations”.
October 15, 2021
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 72,105
Total number of unique gene fusions 32,795
Total number of genes involved 14,023
Enhancements and New Features
Removed the size limit on the search results: User can perform blank searches to retrieve the full data.
View SQL Statements: User can view and utilize the new SQL statement that was used to perform the search.
July 15, 2021
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 71,734
Total number of unique gene fusions 32,721
Total number of genes involved 14,019
Enhancements
Security enhancement (including Data Tables package version update)
April 15, 2021
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 71,298
Total number of unique gene fusions 32,677
Total number of genes involved 14,020
Bug Fixes
Gene Fusion Search failed to return gene fusion results if searched by gene names with a hyphen (‘-’) in it (e.g. ARPC4-TTLL3). This has been fixed.
January 15, 2021
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 71,149
Total number of unique gene fusions 32,618
Total number of genes involved 14,016
October 26, 2020
Bug Fixes
Cases Cytogenetics Searcher: Using ‘Sole Abnormality’ flag with a ‘Breakpoint’ entry will now search cases with karyotypes of sole abnormality with the specified breakpoint.
October 15, 2020
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 70,818
Total number of unique gene fusions 32,578
Total number of genes involved 14,014
July 15, 2020
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 70,469
Total number of unique gene fusions 32,551
Total number of genes involved 14,014
April 15, 2020
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer quarterly update.
Updated totals
Total number of cases 70,236
Total number of unique gene fusions 31,626
Total number of genes involved 13,913
Other changes
New Mitelman Database Logo
August 27, 2019
Initial Release
Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer released on the ISB-CGC platform.
The following searches are available:
Cases Cytogenetics Searcher
Gene Fusions Searcher
Clinical Associations Searcher
Recurrent Chromosome Aberrations Searcher
References Searcher