Exceptional Responders Data Set

About Exceptional Responders

The Exceptional Responders Initiative is a pilot study to investigate the underlying molecular factors driving exceptional treatment responses of cancer patients to drug therapies.

About Exceptional Responders Data

Exceptional Responders has one project EXCEPTIONAL_RESPONDERS-ER with 84 cases spanning nine disease types and 20 primary sites. Data categories include sequencing reads, transcriptome profiling and simple nucleotide variation.

For more information on Exceptional Responders data, please refer to the site below:

Accessing the Exceptional Responders Data on the Cloud

Besides accessing the files on the GDC Data Portal, you can also access them from the GDC Google Cloud Storage Bucket, which means that you don’t need to download them to perform analysis. ISB-CGC stores the cloud file locations in tables in the isb-cgc-bq.GDC_case_file_metadata data set in BigQuery.

  • To access these metadata files, go to the Google BigQuery console.

  • Perform SQL queries to find the Exceptional Responders files. Here is an example:

SELECT active.*, file_gdc_url
FROM `isb-cgc-bq.GDC_case_file_metadata.fileData_active_current` as active, `isb-cgc-bq.GDC_case_file_metadata.GDCfileID_to_GCSurl_current` as GCSurl
AND active.file_gdc_id = GCSurl.file_gdc_id

Accessing the Exceptional Responders Data in Google BigQuery

ISB-CGC has Exceptional Responders data, such as clinical, metadata, RNA-seq and somatic mutation stored in Google BigQuery tables. Information about these tables can be found using the ISB-CGC BigQuery Table Search with EXCEPTIONAL RESPONDERS selected for filter PROGRAM. To learn more about this tool, see the ISB-CGC BigQuery Table Search documentation.

The Exceptional Responders tables are in project isb-cgc-bq. To learn more about how to view and query tables in the Google BigQuery console, see the ISB-CGC BigQuery Tables documentation.

  • Data set isb-cgc-bq.EXC_RESPONDERS contains the latest tables for each data type.

  • Data set isb-cgc-bq.EXC_RESPONDERS_versioned contains previously released tables, as well as the most current table.

Have feedback or corrections? Please email us at feedback@isb-cgc.org.