About the NCI Center for Cancer Research

The NCI Center for Cancer Research (NCICCR) conducted a study on the Genomic Variation in Diffuse Large B Cell Lymphomas (DLBCL) through an integrative analysis of genetic lesions in 574 diffuse large B cell lymphomas (DLBCL). The study investigated genomic structural variation, genetic alteration, and its effect on the development and biology of lymphomas by using high throughput sequencing, gene expression, and methylation status.

About the NCI Center for Cancer Research Data

There were around 489 cases that were phenotyped, contributing Authorized-Access, individual-level data. The Genomic Data Commons currently has around 957 controlled access BAM files available. The Project ID in the GDC Data Portal is NCICCR-DLBCL.

For more information on the NCICCR data, please refer to these sites:

Accessing the NCI Center for Cancer Research Data on the Cloud

Besides accessing the files on the GDC Data Portal, you can also access them from the GDC Google Cloud Storage Bucket, which means that you don’t need to download them to perform analysis. ISB-CGC stores the cloud file locations in tables in the isb-cgc-bq.GDC_case_file_metadata data set in BigQuery.

  • To access these metadata files, go to the Google BigQuery console.
  • Perform SQL queries to find the NCICCR files. Here is an example:
SELECT active.*, file_gdc_url
FROM `isb-cgc-bq.GDC_case_file_metadata.fileData_active_current` as active, `isb-cgc-bq.GDC_case_file_metadata.GDCfileID_to_GCSurl_current` as GCSurl
WHERE program_name = 'NCICCR'
AND active.file_gdc_id = GCSurl.file_gdc_id

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