TRIO Data Set

About TRIO

The Ukrainian National Research Center for Radiation Medicine Trio Study contains epidemiologic data of trios of parents (exposed to the radiation from the Chernobyl accident) and their unexposed offspring. The purpose of the study is to investigate the transgenerational effects following nuclear accidents to understand the consequences of parental exposure to ionizing radiation.

About the TRIO Data

The TRIO data set includes whole genome sequencing (WGS) sequencing reads for 339 cases in the project TRIO-CRU.

For more information on TRIO data, please refer to the site below:

Accessing the TRIO Data on the Cloud

Besides accessing the files on the GDC Data Portal, you can also access them from the GDC Google Cloud Storage Bucket, which means that you don’t need to download them to perform analysis. ISB-CGC stores the cloud file locations in tables in the isb-cgc-bq.GDC_case_file_metadata data set in BigQuery.

  • To access these metadata files, go to the Google BigQuery console.

  • Perform SQL queries to find the TRIO files. Here is an example:

SELECT active.*, file_gdc_url
FROM `isb-cgc-bq.GDC_case_file_metadata.fileData_active_current` as active, `isb-cgc-bq.GDC_case_file_metadata.GDCfileID_to_GCSurl_current` as GCSurl
WHERE program_name = 'TRIO'
AND active.file_gdc_id = GCSurl.file_gdc_id

Accessing the TRIO Data in Google BigQuery

ISB-CGC has TRIO data, such as clinical and metadata, stored in Google BigQuery tables. Information about these tables can be found using the ISB-CGC BigQuery Table Search with TRIO selected for filter PROGRAM. To learn more about this tool, see the ISB-CGC BigQuery Table Search documentation.

The TRIO tables are in project isb-cgc-bq. To learn more about how to view and query tables in the Google BigQuery console, see the ISB-CGC BigQuery Tables documentation.

  • Data set isb-cgc-bq.TRIO contains the latest tables for each data type.

  • Data set isb-cgc-bq.TRIO_versioned contains previously released tables, as well as the most current table.

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